Product Information
- 3-Nitropropanoate
- 3-Nitropropanoic acid
- Bovinocidin
- Hiptagenic acid
- NSC 64266
- Propanoic acid, 3-nitro-
- Propionic acid, 3-nitro-
- β-Nitropropionic acid
3-Nitropropionic acid (3NPA) is a mitochondrial toxin that causes neuronal death by inhibiting complex enzyme activities and inducing reactive oxygen species production. 3NPA also alters mitochondrial membrane potential and induces pro-apoptotic protein expression, leading to neuronal cell death. 3NPA has been shown to be effective in the treatment of experimental models of infectious diseases, such as rat sepsis and human HIV infection, by reducing the number of activated T cells and CD4+ T cells. 3NPA also exhibits anti-inflammatory properties by inhibiting the inflammatory responses of monocytes/macrophages and neutrophils.
Chemical properties
Technical inquiry about: 3D-FN15632 3-Nitropropionic acid
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