N-Nitroso-3-azabicyclo[3.3.0]octane

CAS: 54786-86-6

Ref. 3D-FN166610

Product Information

• Name: N-Nitroso-3-azabicyclo[3.3.0]octane
• Synonyms: Gliclazide impurity B, 2-Nitroso-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole, 2-Nitroso-octahydrocyclopenta[c]pyrrole, 2-Nitrosooctahydrocyclopenta[C]Pyrrole, 3-Nitroso-3-azabicyclo[3.3.0]octane, Cyclopenta[c]pyrrole, octahydro-2-nitroso-, Octahydro-2-nitrosocyclopenta(c)pyrrole, Octahydro-2-nitrosocyclopenta[c]pyrrole

Description

N-Nitroso-3-azabicyclo[3.3.0]octane is a nitrosating agent that can be used for the determination of gliclazide in pharmaceuticals and other applications. It is synthesized by reacting 3-azabicyclo[3.3.0]octane with sodium nitrite in an alkaline environment, followed by hydrolysis with hydrochloric acid. Nitrosation reactions are usually slow, but N-nitroso-3-azabicyclo[3.3.0]octane has been shown to have a fast reaction kinetics, which makes it useful for the determination of gliclazide in pharmaceuticals and other applications. The product is analyzed using chromatographic techniques such as high performance liquid chromatography (HPLC) or gas chromatography/mass spectrometry (GC/MS). The product was found to be linear over the range of 0-

• Brand: Biosynth

Chemical properties

• Molecular weight: 140.18 g/mol
• Formula: C₇H₁₂N₂O
• Purity: Min. 95%
• Color/Form: Colorless Powder
• InChI: InChI=1S/C7H12N2O/c10-8-9-4-6-2-1-3-7(6)5-9/h6-7H,1-5H2
• InChI key: InChIKey=FSCBDDOKZIRLCN-UHFFFAOYSA-N
• SMILES: O=NN1CC2CCCC2C1