Nemadipine B

CAS: 79925-38-5

Ref. 3D-FN26179

Product Information

• Name: Nemadipine B
• Synonyms: 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-diethyl ester

Description

Nemadipine B is a synthetic drug that has been shown to have an antioxidant effect. It binds to the hydrophobic pocket of the cytochrome P450 enzyme, causing activation of this protein. Nemadipine B also inhibits chloride channels and prevents the formation of acid, which is necessary for the degradation of lipids. This drug has been shown to have a hemolytic activity in vitro and in vivo. The reaction products of nemadipine B consist mainly of phenylacetic acid, acetophenone, and 2-hydroxy-5-(2-methylpropyl)benzaldehyde with small amounts of carbon dioxide and water. Nemadipine B is a blocker for l-type calcium channels that can be used for treatment of cardiac arrhythmia.

• Brand: Biosynth

Chemical properties

• Molecular weight: 398.28 g/mol
• Formula: C₁₉H₂₁Cl₂NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C19H21Cl2NO4/c1-5-25-18(23)14-10(3)22-11(4)15(19(24)26-6-2)16(14)12-8-7-9-13(20)17(12)21/h7-9,16,22H,5-6H2,1-4H3
• InChI key: InChIKey=BLLWOXSSRQPDAT-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1cccc(Cl)c1Cl