Nicotinic acid N-hydroxysuccinimide ester

CAS: 78348-28-4

Ref. 3D-FN26209

Product Information

• Name: Nicotinic acid N-hydroxysuccinimide ester
• Synonyms: 3-Pyridinecarboxylic acid 2,5-dioxo-1-pyrrolidinyl ester, 2,5-Pyrrolidinedione, 1-[(3-pyridinylcarbonyl)oxy]-

Description

Nicotinic acid N-hydroxysuccinimide ester is an amide that is used as a precursor in the synthesis of chemokines. It can be used to radiolabel chemokines for detection with a gamma counter or by using metal hydroxides for their radioactive properties. Nicotinic acid N-hydroxysuccinimide ester has been shown to form disulfide bonds, which are important for the physiological function of proteins. This compound reacts with pyridinium ions and releases hydrogen sulfide gas, which can be detected by reaction with ferrous sulfate and ammonium persulfate in a plasma mass spectrometer.

• Brand: Biosynth

Chemical properties

• Molecular weight: 220.18 g/mol
• Formula: C₁₀H₈N₂O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H8N2O4/c13-8-3-4-9(14)12(8)16-10(15)7-2-1-5-11-6-7/h1-2,5-6H,3-4H2
• InChI key: InChIKey=CWBHSNGMXKJGSM-UHFFFAOYSA-N
• SMILES: O=C(ON1C(=O)CCC1=O)c1cccnc1