3-Nitrophthalic anhydride

CAS: 641-70-3

Ref. 3D-FN26343

Product Information

• Name: 3-Nitrophthalic anhydride
• Synonyms: 4-Nitro-2-benzofuran-1,3-dione
• Brand: Biosynth
• Description: 3-Nitrophthalic anhydride is a nucleophilic compound that is activated by the addition of hydrochloric acid and chloride. It reacts with dimethyl formamide to produce nitrobenzene, which can be oxidized to nitrobenzoic acid. 3-Nitrophthalic anhydride has been used as a precursor for pomalidomide, a drug used in the treatment of multiple myeloma and other cancers. In this reaction, n-dimethyl formamide reacts with 3-nitrophthalic anhydride to produce nitromethane, which can then be oxidized to nitrobenzoic acid. Molecular modeling studies have shown that 3-nitrophthalic anhydride binds to DNA through hydrogen bonding interactions and the formation of covalent bonds. The solubility data for 3-nitrophthalic anhydride show that it is soluble in water and organic solvents such as acetone or met

Chemical properties

• Molecular weight: 193.11 g/mol
• Formula: C₈H₃NO₅
• Purity: Min. 85%
• Color/Form: Powder