(R,S)-N-Nitroso anatabine

CAS: 887407-16-1

Ref. 3D-FN26349

Product Information

• Name: (R,S)-N-Nitroso anatabine
• Synonyms: 1,2,3,6-Tetrahydro-1-nitroso-2,3'-bipyridine
• Brand: Biosynth
• Description: (R,S)-N-Nitroso anatabine is a nitrosamine that is used as an analytical standard for the determination of the covalent binding of carcinogens to DNA. It can be synthesized by reacting (R,S)-N-nitrosodimethylamine with nitric acid in the presence of aluminum chloride. The structure and purity of this compound were confirmed by LC-MS/MS. The compound was found to be carcinogenic when administered to female mice, but not male mice. The carcinogenicity was attributed to the formation of DNA adducts in tissues and the induction of chromosomal aberrations.

Chemical properties

• Molecular weight: 189.21 g/mol
• Formula: C₁₀H₁₁N₃O
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C10H11N3O/c14-12-13-7-2-1-5-10(13)9-4-3-6-11-8-9/h1-4,6,8,10H,5,7H2
• InChI key: InChIKey=ZJOFAFWTOKDIFH-UHFFFAOYSA-N
• SMILES: O=NN1CC=CCC1c1cccnc1