Norgestrel

CAS: 6533-00-2

Ref. 3D-FN26455

Product Information

• Name: Norgestrel
• Synonyms: (17a)-(+/-)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one(+/-)-13-Ethyl-17a-ethynyl-17-hydroxygon-4-en-3-one, (.+-.)-13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one, (.+-.)-17α-Ethynyl-13-ethyl-17-hydroxygon-4-en-3-one, (.+-.)-17α-Ethynyl-13β-ethylgon-4-en-17β-ol-3-one, (.+-.)-Norgestrel, (17α)-(±)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one, 13-Ethyl-17α-ethynyl-17β-hydroxy-4-gonen-3-one, 18,19-Dinor-17α-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (.+-.)-, <span class="text-smallcaps">DL</span>-Norgestrel, DL-Norgestrel, Fh 122A, Methylnorethindrone, Monovar, Neogest, Ovrette, Postinor, Sh 70850, Sh 850, Wy 3707, dl-11β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one, dl-13-β-Ethyl-17-α-ethynyl-17-β-hydroxygon-4-en-3-one, α-Norgestrel, 13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name), Norgestrel [USAN:INN:BAN:JAN], 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-,(17alpha)-(+-)-, Norgestrel (DL-), (8R,9S,10R,13S,14S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name), (+-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one, dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone, 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)-, 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-(±)-, (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name), dl-13-beta-Ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one, (10R,13S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)

Description

Norgestrel is a synthetic progestin that is used in hormonal contraceptives. It is also used to treat endometriosis, uterine bleeding, and other conditions. Norgestrel has been found to bind to the progesterone receptor and inhibit the secretion of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH). This drug also inhibits hepatic lipase activity and may reduce body mass index by increasing lipid metabolism. Basic fibroblasts incubated with nomegestrol acetate show an increased production of leukemia inhibitory factor (LIF) and neurotrophic factors that are important for cell growth and differentiation. These effects have not been seen in women using this drug for contraception, but have been observed in untreated groups of women.br>
Norgestrel is a steroidal progestin which has been shown to increase the number of leukocytes in the uterus, particularly

• Brand: Biosynth

Chemical properties

• Molecular weight: 312.45 g/mol
• Formula: C₂₁H₂₈O₂
• Purity: Min. 95%