Nequinate

CAS: 13997-19-8

Ref. 3D-FN40622

Product Information

• Name: Nequinate
• Brand: Biosynth
• Description: Nequinate is an amide that is an inhibitor of microbial protein synthesis. It binds to the ribosomal 30S subunit and inhibits bacterial growth by inhibiting the binding of aminoacyl-tRNA to the ribosomal A site. Nequinate also inhibits the synthesis of bacterial cell wall polymers and has antimicrobial activity against a number of Gram-positive and Gram-negative bacteria. It is not active against fungi, protozoa, or viruses. Nequinate can be used as a fluorescent dye with a fluorescence detector for biological samples such as blood, urine, cerebrospinal fluid, or other body fluids. In addition, nequinate inhibits benzalkonium chloride-induced hemolysis in human erythrocytes. Nequinate also has been shown to inhibit metabolic disorders such as congestive heart failure and diabetes in animal models.

Chemical properties

• Molecular weight: 365.42 g/mol
• Formula: C₂₂H₂₃NO₄
• Purity: Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C22H23NO4/c1-3-4-10-16-11-17-19(23-13-18(21(17)24)22(25)26-2)12-20(16)27-14-15-8-6-5-7-9-15/h5-9,11-13H,3-4,10,14H2,1-2H3,(H,23,24)
• InChI key: InChIKey=NNOPDLNHPOLRRE-UHFFFAOYSA-N
• SMILES: CCCCc1cc2c(=O)c(C(=O)OC)c[nH]c2cc1OCc1ccccc1