Nequinate

CAS: 13997-19-8

Ref. 3D-FN40622

Product Information

• Name: Nequinate
• Synonyms: 3-Quinolinecarboxylic acid, 6-butyl-1,4-dihydro-4-oxo-7-(phenylmethoxy)-, methyl ester, 3-Quinolinecarboxylic acid, 7-(benzyloxy)-6-butyl-1,4-dihydro-4-oxo-, methyl ester, 6-Butyl-1,4-Dihydro-4-Oxo-7-(Phenyl Methoxy)-3-Quinolinecarboxylic Acid Methyl Ester, 6-Butyl-1,4-Dihydro-4-Oxo-7-(Phenylmethoxy)-3-Quinolinecarboxylic Acid Methyl Ester, 7-Benzyloxy-6-butyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid methyl ester, Ay 20385, Ici 55052, Mequinate, Methyl 7-(Benzyloxy)-6-Butyl-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate, Methyl 7-(benzyloxy)-6-butyl-1,4-dihydro-4-oxo-3-quinoline carboxylate, Methyl 7-(benzyloxy)-6-n-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylate, Methyl benzoquate, Methylbenzoquate Nequinate, Neqoinate, Statil, Statoquate, Statyl, Statyl statil Statoquate Tranil, Tranil

Description

Nequinate is an amide that is an inhibitor of microbial protein synthesis. It binds to the ribosomal 30S subunit and inhibits bacterial growth by inhibiting the binding of aminoacyl-tRNA to the ribosomal A site. Nequinate also inhibits the synthesis of bacterial cell wall polymers and has antimicrobial activity against a number of Gram-positive and Gram-negative bacteria. It is not active against fungi, protozoa, or viruses. Nequinate can be used as a fluorescent dye with a fluorescence detector for biological samples such as blood, urine, cerebrospinal fluid, or other body fluids. In addition, nequinate inhibits benzalkonium chloride-induced hemolysis in human erythrocytes. Nequinate also has been shown to inhibit metabolic disorders such as congestive heart failure and diabetes in animal models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 365.42 g/mol
• Formula: C₂₂H₂₃NO₄
• Purity: Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C22H23NO4/c1-3-4-10-16-11-17-19(23-13-18(21(17)24)22(25)26-2)12-20(16)27-14-15-8-6-5-7-9-15/h5-9,11-13H,3-4,10,14H2,1-2H3,(H,23,24)
• InChI key: InChIKey=NNOPDLNHPOLRRE-UHFFFAOYSA-N
• SMILES: CCCCc1cc2c(=O)c(C(=O)OC)c[nH]c2cc1OCc1ccccc1