Nesiritide acetate

CAS: 124584-08-3

Ref. 3D-FN41185

Product Information

• Name: Nesiritide acetate
• Synonyms: Natriureticfactor-32 (human brain clone lhBNP57), 1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecaazacyclotripentacontane,cyclic peptide deriv., 1: PN:US6028055 SEQID: 1 claimed protein, 6: PN:US20090011997 SEQID: 4 claimed protein, 83: PN: US20080153747 SEQID: 83 claimedprotein, Human brain natriuretic factor-32, Human brain natriuretic peptide-32, L-Histidine,L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminylglycyl-L-serylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-arginyl-L-lysyl-L-methionyl-L-a-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-,cyclic (10?, 26)-Disulfide, Natriureticpeptide type-B, Nesiritide, BNP-32 (human)

Description

Nesiritide acetate is a man-made form of the natriuretic peptide hormone that is secreted by the heart. It is used to treat high blood pressure and congestive heart failure. Nesiritide acetate increases the amount of sodium and water excreted from the body, which reduces blood volume and lowers blood pressure. It also relaxes blood vessels, leading to lower blood pressure. This drug can also be used in diagnosis to assess levels of natriuretic peptides in the bloodstream. The typical therapeutic dose for this drug is 100 mcg/kg given intravenously over 30 minutes and then infusion at 0.01 mcg/kg/min for up to 24 hours. The dosage may be increased or decreased depending on the severity of symptoms or side effects experienced by the patient.

• Brand: Biosynth

Chemical properties

• Molecular weight: 3,464.05 g/mol
• Formula: C₁₄₃H₂₄₄N₅₀O₄₂S₄•(C₂H₄O₂)x
• Purity: Min. 95 Area-%
• Color/Form: Powder