H-Trp(Boc)-OH

CAS: 146645-63-8

Ref. 3D-FN48185

Product Information

• Name: H-Trp(Boc)-OH
• Synonyms: N-Boc-L-tryptophan, 1-(tert-butoxycarbonyl)-L-tryptophan, 1-Boc-<span class="text-smallcaps">L</span>-tryptophan, 1-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tryptophan, <span class="text-smallcaps">L</span>-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-, N-In-Boc-L-Tryptophan, N-Indole-T-Butoxycarbonyl-L-Tryptophan

Description

H-Trp(Boc)-OH is an antiproliferative molecule that has been synthesized as a template molecule for the synthesis of analogs. It has been found to have cytotoxic and antiproliferative effects on cancer cells in culture. H-Trp(Boc)-OH is an enantiomer of the natural amino acid, tryptophan, and was postulated to be able to inhibit tumor growth by alkylation. This compound can also be synthesized using a solid-phase synthesis. H-Trp(Boc)-OH is an analog of desotamide, which inhibits the enzyme DNA polymerase α that catalyzes the conversion of deoxyribonucleoside triphosphates into DNA. The chloride ion in this compound may be responsible for its cytotoxic effects on cancer cells in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 304.34 g/mol
• Formula: C₁₆H₂₀N₂O₄
• Purity: Min. 95%
• Color/Form: White/Off-White Solid