D-His(Bzl)-OH

CAS: 2022956-35-8

Ref. 3D-FN48686

Product Information

• Name: D-His(Bzl)-OH
• Synonyms: Nim-Benzyl-D-histidine
• Brand: Biosynth
• Description: D-His(Bzl)-OH is a chromatographic ligand that has been used in the preparation of recombinant proteins and vaccines. D-His(Bzl)-OH is an amphipathic molecule with a hydrophilic head group and hydrophobic tail group. It has been shown to be an effective inhibitor of papillomavirus, as well as other viruses such as HIV, herpes simplex virus, poliovirus, and vesicular stomatitis virus. D-His(Bzl)-OH has also been shown to induce antibody production in micelles when conjugated to antigens. The binding of D-His(Bzl)-OH to the viral envelope protein can be increased by increasing pH or by adding ammonium sulfate or chloride ions. Increasing the flow rate during chromatography will also increase the progressions of D-His(Bzl)-OH through the column.

Chemical properties

• Molecular weight: 245.28 g/mol
• Formula: C₁₃H₁₅N₃O₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C13H15N3O2/c14-12(13(17)18)6-11-8-16(9-15-11)7-10-4-2-1-3-5-10/h1-5,8-9,12H,6-7,14H2,(H,17,18)
• InChI key: InChIKey=NMXSWQMJOZUQKY-UHFFFAOYSA-N
• SMILES: NC(Cc1cn(Cc2ccccc2)cn1)C(=O)O