Product Information
- 4-Nitrophenoxyacetic acid
- (4-Nitrophenoxy)acetic acid
- (p-Nitrophenoxy)acetic acid
- Acetic acid, (4-nitrophenoxy)-
- Acetic acid, 2-(4-nitrophenoxy)-
- Acetic acid, p-nitrophenoxy-
- Ai3-52610
- Ba 2690
- Brn 2051970
- Nsc 166278
- See more synonyms
- p-Nitrophenoxyacetic acid
- α-(4-Nitrophenoxy)acetic acid
2-(4-Nitrophenoxy)acetic acid is a chemical compound with the molecular formula CHNO. It has been shown to inhibit the polymerase chain reaction, which is an important technique in molecular biology. The intramolecular hydrogen bond between HN and OO stabilizes the molecule and inhibits its rotation. This allows 2-(4-Nitrophenoxy)acetic acid to function as a competitive inhibitor of DNA polymerase. 2-(4-Nitrophenoxy)acetic acid inhibits bacterial growth by binding to the beta subunit of DNA gyrase, an enzyme that maintains the integrity of bacterial DNA. This inhibition prevents topoisomerase IV from relaxing supercoiled DNA, leading to cell death by inhibiting protein synthesis and cell division.
Chemical properties
Technical inquiry about: 3D-FN55024 2-(4-Nitrophenoxy)acetic acid
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