Nitidine chloride

CAS: 13063-04-2

Ref. 3D-FN65676

Product Information

• Name: Nitidine chloride
• Synonyms: 2,3-Dimethoxy-12-Methyl-3,12-Dihydro[1,3]Benzodioxolo[5,6-C]Phenanthridine, 2,3-Dimethoxy-12-Methyl[1,3]Benzodioxolo[5,6-C]Phenanthridin-12-Ium, 2,3-Dimethoxy-12-Methyl[1,3]Benzodioxolo[5,6-C]Phenanthridin-12-Ium Chloride, 2,3-Dimethoxy-12-methyl-(1,3)-benzodioxolo(5,6-c)phenanthridinium chloride, Dimethoxy-12-Methyl-,Chloride, NSC 146397, Nitidine, Sml 0610, [1,3]Benzodioxolo[5,6-c]phenanthridinium, 2,3-dimethoxy-12-methyl-, chloride, [1,3]Benzodioxolo[5,6-c]phenanthridinium, 2,3-dimethoxy-12-methyl-, chloride (1:1), [1,3]Dioxolo[4,5]benzo[1,2-c]phenanthridinium, 2,3-

Description

Nitidine chloride is a potent inducer of energy metabolism and has been shown to stimulate the growth of cells in tissue culture. It is also active against cancer cells, and has been shown to decrease cell proliferation, induce apoptosis, and inhibit angiogenesis. Nitidine chloride has been shown to be an inhibitor of protein synthesis by binding to the polymerase chain reaction (PCR) enzyme. Nitidine chloride can also affect cell nuclei by inhibiting DNA replication. The mechanism of action for nitidine chloride is not fully understood but may be due to its ability to bind with DNA or RNA in cells. This binding inhibits transcription and translation processes, leading to inhibition of protein synthesis and cell death. Nitidine chloride is found naturally in plants such as Ginkgo biloba and Acorus calamus. The compound can be synthesized from chloroacetamide, a natural compound that is produced by bacteria such as Corynebacterium glutamicum.

• Brand: Biosynth

Chemical properties

• Molecular weight: 383.82 g/mol
• Formula: C₂₁H₁₈ClNO₄
• Purity: Min. 95%
• Color/Form: Powder