beta-Naphthamide

CAS: 2243-82-5

Ref. 3D-FN67204

Product Information

• Name: beta-Naphthamide
• Synonyms: Naphthalene-2-carboxamide, 2-Naphthalenecarboxamide, 2-Naphthamide, 2-Naphthylamide, NSC 171209

Description

Beta-naphthamide is an inhibitor binding to the dinucleotide phosphate (DNP) in bacterial cells. This binding prevents the enzyme from carrying out its normal function, which is the production of ATP, and it also inhibits various other enzymes. Beta-naphthamide inhibits the growth of Gram-positive bacteria by inhibiting their cell wall assembly and also has a bactericidal effect on Gram-negative bacteria. Beta-naphthamide has been shown to be active against multidrug efflux pump proteins that are present in Gram-negative bacteria, such as Escherichia coli. DNP is a receptor for dopamine and beta-naphthamide inhibits dopamine receptors in mammalian cells, which may lead to Parkinson's disease. Beta-naphthamide has been shown to inhibit the polymerase chain reaction (PCR) mechanism by binding to DNA polymerase. Beta-naphthamide binds to receptors on trigeminal nerve endings, which leads to paralysis of

• Brand: Biosynth

Chemical properties

• Molecular weight: 171.2 g/mol
• Formula: C₁₁H₉NO
• Purity: Min. 95%
• InChI: InChI=1S/C11H9NO/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H2,12,13)
• InChI key: InChIKey=JVXXKQIRGQDWOJ-UHFFFAOYSA-N
• SMILES: NC(=O)c1ccc2ccccc2c1