Product Information
Name:Nodularin
Brand:Biosynth
Description:Nodularin is an indolic alkaloid that has been identified as a potent inhibitor of the mitogen-activated protein kinase (MAPK) pathway. It has been shown to inhibit the growth factor-β1 and platelet-derived growth factor (PDGF)-induced proliferation of vascular smooth muscle cells in vitro. Nodularin can be used to detect MAPK activation by using Western blotting with phosphorylated extracellular signal regulated kinase 1/2 (ERK1/2) antibodies. In addition, nodularin can be used for the detection of intracellular targets, such as cyclic AMP response element binding protein (CREB), which is activated by CREB-binding protein and phosphatidylinositol 3-kinase.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:824.96 g/mol
Formula:C41H60N8O10
Purity:Min. 95%
Color/Form:Powder
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