Neuromedin U, rat

Ref. 3D-FN73510

Product Information

• Name: Neuromedin U, rat
• Brand: Biosynth
• Description: Neuromedin U is a peptide that has been found to have high binding affinity for 5-hydroxytryptamine (5-HT)2 receptors. Neuromedin U is also able to activate locomotor activity in rats, and has been shown to inhibit the growth of mammalian carcinoma cells in culture. This peptide binds to the 5-HT2 receptor and inhibits adenylyl cyclase activity, leading to a decrease in intracellular levels of cAMP and cytosolic Ca2+. The physiological effects of neuromedin U are mediated through its ability to stimulate pluripotent cells in the brain, as well as its ability to inhibit energy metabolism. Neuromedin U has also been shown to bind to polymerase chain reaction (PCR) primers, suggesting it may be used as a probe for DNA sequencing or gene mapping.

Chemical properties

• Molecular weight: 2,642.97 g/mol
• Formula: C₁₂₄H₁₈₀N₃₄O₃₁
• Purity: Min. 95%