6-Oxo boldione

CAS: 72648-46-5

Ref. 3D-FO26640

Product Information

• Name: 6-Oxo boldione
• Synonyms: Androsta-1,4-diene-3,6,17-trioneFCE 24204(8R,9S,10R,13S,14S)-10,13-Dimethyl-7,8,9,11,12,13,15,16-octahydro-10H-cyclopenta[a]phenan threne-3,6,17(14H)-trione
• Brand: Biosynth
• Description: 6-Oxo boldione is an aromatase inhibitor that inhibits the conversion of testosterone to estradiol and has been shown to be effective in inhibiting the growth of bacteria such as Typhimurium. 6-Oxo boldione has been shown to inhibit the growth of estrogen-sensitive breast cancer cells in vitro. It also has a dose-dependent effect on rat liver microsomes, with a greater inhibition at high doses. This drug may be metabolized by modification of its side chain or by biotransformation. 6-Oxo boldione is not active against other enzymes such as cytochrome P450 or glutathione S-transferases.

Chemical properties

• Molecular weight: 298.38 g/mol
• Formula: C₁₉H₂₂O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H22O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h5,7,9,12-14H,3-4,6,8,10H2,1-2H3/t12-,13-,14-,18+,19-/m0/s1
• InChI key: InChIKey=BXPQXTJWPDQYMP-IEVKOWOJSA-N
• SMILES: C[C@]12C=CC(=O)C=C1C(=O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12