Oxybutynin N-oxide

CAS: 80976-68-7

Ref. 3D-FO26702

Product Information

• Name: Oxybutynin N-oxide
• Synonyms: a-Cyclohexyl-a-hydroxybenzeneacetic acid 4-(diethyloxidoamino)-2-butyn-1-yl ester
• Brand: Biosynth
• Description: Oxybutynin N-oxide is a synthetic drug that belongs to the class of antispasmodics. It inhibits bladder contractions by blocking acetylcholine receptors. Oxybutynin N-oxide is metabolized in rat liver microsomes and the metabolic conversion yields oxybutynin and oxobutynin as the major metabolites, although other metabolites such as n-oxides are also observed. The metabolic conversion is controlled by cytochrome P450 enzymes. The oral bioavailability of oxybutynin N-oxide is low due to its low solubility in water and lack of a charged functional group in its structure, which makes it a poor substrate for drug transporters. The chemical stability of oxybutynin N-oxide has been shown to be high, even at elevated temperatures or when it is exposed to light or air. Oxybutynin N-oxide is not absorbed orally and must be administered intravenously or by rectal suppository.

Chemical properties

• Molecular weight: 373.49 g/mol
• Formula: C₂₂H₃₁NO₄
• Purity: 90%Min