Product Information
- 1H-Imidazole-4-carboxamide, 5-amino-, mono(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylate)
- 4-Amino-5-imidazolecarboxamide orotate
- 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, compd. with 5-amino-1H-imidazole-4-carboxamide (1:1)
- 4-amino-1H-imidazole-5-carboxamide,2,4-dioxo-1H-pyrimidine-6-carboxylic acid,dihydrate
- 5-Aminoimidazole-4-carboxamide orotate
- AICA orotate
- AICA-hepat
- Aicamin
- Aicorat
- Ba 2757
- See more synonyms
- Orazamid
- Orazamide orotate
- Orotic acid, compd. with 5(or 4)-aminoimidazole-4(or 5)-carboxamide
- Orotic acid, compd. with 5-aminoimidazole-4-carboxamide (1:1)
Orazamide is a piperazine derivative that is used in the treatment of high blood pressure. It works by binding to the skeleton and the liver, preventing the accumulation of sodium and chloride ions. This results in a decrease in blood pressure. Orazamide has been shown to decrease insulin resistance and also has an important role in the prevention of symptoms such as edema, headache, dizziness, nausea, vomiting, and fatigue. It also has a diuretic effect on the kidneys with sodium citrate as its main excipient. The chlorine atom binds to the heterocycle group to form a coordination complex that can bind to heme proteins, thus inhibiting its function.
Orazamide is an analog of chlorothiazide with a chlorine atom replacing one oxygen atom on the heterocycle group.
Chemical properties
Technical inquiry about: 3D-FO65114 Orazamide
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