1-Piperonylpiperazine

CAS: 32231-06-4

Ref. 3D-FP02697

Product Information

• Name: 1-Piperonylpiperazine
• Synonyms: 1-(1,3-Benzodioxol-5-Ylmethyl)Piperazine, 1-(1,3-Benzodioxol-5-Ylmethyl)Piperazinediium, 1-(1,3-Benzodioxol-5-ylmethyl)piperazin, 1-(1,3-Benzodioxolan-5-ylmethyl)piperazine, 1-(3,4-Methylenedioxybenzyl)piperazine, 1-(3,4-Methylenedioxyphenylmethyl)piperazine, 1-(4-Piperonyl)piperazine, 1-(Benzo[1,3]dioxol-5-ylmethyl)piperazine, 1-(Benzodioxol-5-ylmethyl)piperazine, 1-[(1,3-Dioxaindan-5-yl)methyl]piperazine, 1-[(2H-1,3-Benzodioxol-5-yl)methyl]piperazine, 1-[(Benzo[d][1,3]dioxol-5-yl)methyl]piperazine, 32231-06-4, 4-(4-Piperonyl)piperazine, 4-[(1,3-Benzodioxol-5-yl)methyl]piperazine, 4-[(Benzodioxol-5-yl)methyl]piperazine, 5-(Piperazinomethyl)-1,3-benzodioxole, N-(3,4-Methylenedioxybenzyl)piperazine, N-Piperonylpiperazine, N-[(1,3-Benzodioxol-5-yl)methyl]piperazine, Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-, Piperazine, 1-piperonyl-

Description

1-Piperonylpiperazine is a drug that is used to treat symptoms of diabetic neuropathy. It is an inhibitor of mitochondrial ATPases and blocks the synthesis of nucleotides in the liver. It also inhibits uptake processes in the brain and spinal cord, which are related to locomotor activity. The uptake assays showed that 1-piperonylpiperazine has a high affinity for receptors in the human liver, which could be useful for future research on drugs targeting this organ. 1-Piperonylpiperazine has been shown to have strong effects on mitochondrial membrane potential and ATP levels in primary cells, as well as increasing uptake into human liver cells. This drug may be useful for treating symptoms of diabetic neuropathy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 220.27 g/mol
• Formula: C₁₂H₁₆N₂O₂
• Purity: Min. 95%
• Color/Form: Solid
• InChI: InChI=1S/C12H16N2O2/c1-2-11-12(16-9-15-11)7-10(1)8-14-5-3-13-4-6-14/h1-2,7,13H,3-6,8-9H2
• InChI key: InChIKey=NBOOZXVYXHATOW-UHFFFAOYSA-N
• SMILES: c1cc2c(cc1CN1CCNCC1)OCO2