6-Phenyl-2-thiouracil

CAS: 36822-11-4

Ref. 3D-FP08051

Product Information

• Name: 6-Phenyl-2-thiouracil
• Synonyms: Phenylthiouracil, 2,3-Dihydro-6-phenyl-2-thioxo-4(1H)-pyrimidinone, 2-Mercapto-6-phenyl-1H-pyrimidin-4-one, 2-Mercapto-6-phenylpyrimidin-4-ol, 4(1H)-Pyrimidinone, 2,3-dihydro-6-phenyl-2-thioxo-, 6-Phenylthiouracil, 6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, Ai3-26584, Fenucil, Nsc 163991, Nsc 42600, Uracil, 6-phenyl-2-thio-

Description

6-Phenyl-2-thiouracil (6PTU) is an alkylthio group that inhibits the growth of microorganisms by binding to DNA. 6PTU binds to the oxygen nucleophiles in DNA and prevents transcription and replication. It also has a positive effect on the synthesis of proteins, which may be due to its ability to regulate gene transcription. 6PTU has been shown to inhibit cell growth in culture by blocking protein synthesis. This drug is used as an analytical method for determining urinary glucose levels in animals because it reacts with glucose in urine samples. The reaction produces a chromatographic peak that can be quantified using an electrochemical detector.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.25 g/mol
• Formula: C₁₀H₈N₂OS
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H8N2OS/c13-9-6-8(11-10(14)12-9)7-4-2-1-3-5-7/h1-6H,(H2,11,12,13,14)
• InChI key: InChIKey=XEKNACRTWJHOCE-UHFFFAOYSA-N
• SMILES: O=c1cc(-c2ccccc2)[nH]c(=S)[nH]1