Perfluorooctanesulfonamide

CAS: 754-91-6

Ref. 3D-FP102744

Product Information

• Name: Perfluorooctanesulfonamide
• Synonyms: 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-Octanesulfonamid Ai3-29759, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluoro-1-octanesulfonamide, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluorooctan-1-sulfonamide, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluorooctane-1-Sulfonamide, 1-Octanesulfonamide, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-, Ai 3-29759, Desethylsulfluramid, Heptadecafluorooctanesulphonamide, N-Ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1- octanesulfonamide, Perfluoroalkyl-sulfonamide, Perfluoroctylsulfonamide, Perfluoroocctanesulfonamide, Perfluorooctanesulfonic acid amide, Perfluorooctanesulphonamide, Perfluorooctansulfonamide, Perfluorooctylsulfoamide, Perfluorooctylsulfonamide, Pfosa

Description

Perfluorooctanesulfonamide (PFOS) is an organic compound that is used as a surfactant in fire-fighting foams and metalworking fluids. PFOS is highly toxic to humans and animals, and it can persist for long periods of time in the environment. It has been shown to inhibit the activity of several enzymes, including carboxylesterase, acetylcholinesterase, and butyrylcholinesterase, which are essential for proper functioning of the liver cells. PFOS also inhibits the oxidation of fatty acids by hydroxyl radicals in vitro, leading to lipid peroxidation. Furthermore, PFOS has been shown to be carcinogenic in animal studies. The degradation process for PFOS includes hydrolysis by esterases or glucuronidases and oxidation by cytochrome P450 enzymes or glutathione reductase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 499.15 g/mol
• Formula: C₈H₂F₁₇NO₂S
• Purity: Min. 94%
• Color/Form: Powder
• InChI: InChI=1S/C8H2F17NO2S/c9-1(10,3(13,14)5(17,18)7(21,22)23)2(11,12)4(15,16)6(19,20)8(24,25)29(26,27)28/h(H2,26,27,28)
• InChI key: InChIKey=RRRXPPIDPYTNJG-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F