H-Phe-Trp-OH

CAS: 24587-41-5

Ref. 3D-FP108148

Product Information

• Name: H-Phe-Trp-OH
• Synonyms: 1: PN: EP2161028 PAGE: 9 claimed protein, 37: PN: WO2020097235 SEQID: 266 claimed protein, <span class="text-smallcaps">L</smallcap>-Phenylalanyl-<smallcap>L</span>-tryptophan, <span class="text-smallcaps">L</smallcap>-Tryptophan, <smallcap>L</span>-phenylalanyl-, <span class="text-smallcaps">L</smallcap>-Tryptophan, N-<smallcap>L</span>-phenylalanyl-, Brn 5145119, Dipeptide 4, L-Tryptophan, N-L-phenylalanyl-, L-phenylalanyl-L-tryptophan, Phenylalanyltryptophan, Tryptophan, N-(3-phenyl-<span class="text-smallcaps">L</smallcap>-alanyl)-, <smallcap>L</span>-, Tryptophan, N-(3-phenyl-L-alanyl)-, L-, Tryptophan-L-phenylalanine, L-
• CAS: 24587-41-5

Description

H-Phe-Trp-OH is an inhibitor of protein phosphatase 2A and is used in the diagnosis of kidney cancer. Magnetic resonance spectroscopy (MRS) is a technique that can be used to measure the concentration of phosphate groups in tissues. Hypophosphatemia, or low phosphate levels in the body, is associated with a number of diseases, including kidney cancer. This molecule inhibits the activity of phosphatase 2A and can be used as a diagnostic marker for such conditions. The enzyme has been shown to have an inhibitory effect on vitamin D3-induced synthesis of calcitriol (1,25-dihydroxyvitamin D3), which may be due to its ability to sequester phosphate groups. H-Phe-Trp-OH binds to proteins and has been shown to have an inhibitory effect on other enzymes such as histidine phosphatase and glutamine phosphatase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 351.4 g/mol
• Formula: C₂₀H₂₁N₃O₃
• Purity: Min. 95%
• Color/Form: Powder