H-Pro-Ile-OH

CAS: 51926-51-3

Ref. 3D-FP108157

Product Information

• Name: H-Pro-Ile-OH
• Synonyms: 2003: PN: EP2071334 SEQID: 2112 claimed protein, 2003: PN: WO2009077864 SEQID: 2112 claimed protein, 377: PN: EP2161028 PAGE: 14 claimed protein, 452: PN: WO2005081628 SEQID: 454 claimed protein, <span class="text-smallcaps">L</smallcap>-Isoleucine, <smallcap>L</span>-prolyl-, <span class="text-smallcaps">L</smallcap>-Isoleucine, N-<smallcap>L</span>-prolyl-, <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-isoleucine, L-Prolyl-L-isoleucine, L-prolyl-L-alloisoleucine
• CAS: 51926-51-3

Description

H-Pro-Ile-OH is an amino acid that is found in the mitochondria of cells. It is a prodrug that binds to angiotensin and blocks its conversion to angiotensin II, which has been shown to have blood pressure lowering effects. H-Pro-Ile-OH has been shown to be a competitive inhibitor of oligopeptidase, with a half maximal inhibitory concentration (IC50) of 0.5 mM, and has also been shown to have antihypertensive properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 228.29 g/mol
• Formula: C₁₁H₂₀N₂O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H20N2O3/c1-3-7(2)9(11(15)16)13-10(14)8-5-4-6-12-8/h7-9,12H,3-6H2,1-2H3,(H,13,14)(H,15,16)/t7-,8-,9-/m0/s1
• InChI key: InChIKey=OCYROESYHWUPBP-CIUDSAMLSA-N
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)O