H-Pro-Val-OH

CAS: 52899-09-9

Ref. 3D-FP108165

Product Information

• Name: H-Pro-Val-OH
• Brand: Biosynth
• Description: H-Pro-Val-OH is an amide that is used to treat renal disorders by inhibiting leukocyte elastase. It has been shown to be a potent inhibitor of serine proteases, including chymotrypsin and trypsin. H-Pro-Val-OH binds to the active site on serine proteases and blocks the release of peptides from the enzyme. The binding constant for H-Pro-Val-OH with chymotrypsin was found to be in the range of 3 x 10 M, which is significantly higher than that for other amides. In addition, H-Pro-Val-OH inhibits cytolysis by lysosomal enzymes and protects against liver injury caused by chronic liver disease. This drug also shows low molecular weight and high water solubility, making it effective in treating acute hepatitis.

Chemical properties

• Molecular weight: 214.26 g/mol
• Formula: C₁₀H₁₈N₂O₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H18N2O3/c1-6(2)8(10(14)15)12-9(13)7-4-3-5-11-7/h6-8,11H,3-5H2,1-2H3,(H,12,13)(H,14,15)/t7-,8-/m0/s1
• InChI key: InChIKey=AWJGUZSYVIVZGP-YUMQZZPRSA-N
• SMILES: CC(C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)O