PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt

CAS: 171436-38-7

Ref. 3D-FP109453

Product Information

• Name: PAR-2 (1-6) amide (mouse, rat) trifluoroacetate salt
• Synonyms: H-Ser-Leu-Ile-Gly-Arg-Leu-NH2 H-SLIGRL-NH2, Ser-Leu-Ile-Gly-Arg-Leu-Amide, Sligrlamide, Sligrl-Nh2, Thrombin Receptor-Like 1 (1-6) Amide (Mouse, Rat), Proteinase Activated Receptor 2 (1-6) Amide (Mouse, Rat), Proline/Betaine Transporter Fragment Amide, Par-2 (1-6) Amide (Mouse, Rat), Par2-Ap

Description

PAR-2 agonist is a synthetic peptide that activates PAR-2. It binds to PAR-2 receptors, which are present in the mesenteric vasculature and in various other tissues. Activation of PAR-2 leads to an increase in intracellular calcium concentration, activation of protein kinase C, cytosolic calcium ion release, phosphorylation of myosin light chain, muscle cell proliferation, transcription and translation initiation, and increased production of vasoactive intestinal peptide. This drug also has anti-inflammatory effects and stimulates epidermal growth factor (EGF) and thrombin receptor expression as well as growth factor production.

• Brand: Biosynth

Chemical properties

• Molecular weight: 656.82 g/mol
• Formula: C₂₉H₅₆N₁₀O₇
• Purity: Min. 95%