PAR-2 (6-1) amide (mouse, rat) trifluoroacetate salt
CAS: 245329-01-5
Ref. 3D-FP109860
1mg | 228.00 € | ||
2mg | 371.00 € | ||
5mg | 658.00 € | ||
10mg | 1,027.00 € | ||
25mg | 2,233.00 € |
Product Information
- H-Leu-Arg-Gly-Ile-Leu-Ser-NH2 H-LRGILS-NH2
PAR-2 (6-1) amide is a proteolytic enzyme that is activated by inflammatory stimuli. It has been shown to be a major contributor to the pathogenesis of inflammatory bowel disease, and is found in neurons, the bowel, and pancreatic acinar cells. PAR-2 (6-1) amide activates proteases such as trypsin and chymotrypsin and also functions as an antimicrobial peptide. Activation of PAR-2 (6-1) amide leads to the cleavage of proteins at specific sites on their amino acid chains. This cleavage can lead to changes in protein conformation or function. PAR-2 (6-1) amide has been shown to increase endothelial cell proliferation and inhibit bacterial growth, but does not have any effect on cultured normal human skin fibroblasts.
Chemical properties
Technical inquiry about: 3D-FP109860 PAR-2 (6-1) amide (mouse, rat) trifluoroacetate salt
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