pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt

CAS: 112955-31-4

Ref. 3D-FP110380

Product Information

• Name: pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt
• Synonyms: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser -Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-T hr-Ala-NH2 H-AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTA-NH2
• Brand: Biosynth
• Description: Parathyroid hormone-related protein (PTHrP) is a peptide hormone produced by the parathyroid gland that functions as a phosphatase, inhibiting alkaline phosphatase. It also has an inhibitory effect on osteoclastic bone resorption and stimulates osteoblastic bone formation. PTHrP has been shown to be useful in treating osteoporosis and Paget's disease. It also has been used in conjunction with dexamethasone to treat patients with malignancies of the head and neck. PTHrP is an inhibitor of protein kinase A and phosphodiesterases, which are enzymes that regulate cellular processes such as proliferation and differentiation.

Chemical properties

• Molecular weight: 4,016.58 g/mol
• Formula: C₁₈₀H₂₈₈N₅₈O₄₇
• Purity: Min. 95%