Z-Pro-Pro-aldehyde-dimethyl acetal

CAS: 170116-63-9

Ref. 3D-FP111060

Product Information

• Name: Z-Pro-Pro-aldehyde-dimethyl acetal
• Brand: Biosynth
• Description: Z-Pro-Pro-aldehyde-dimethyl acetal is a neurotoxin that can be used to label lysosomal enzymes in cells. The labeling is stable and does not interfere with the enzymatic activity of the enzyme. It has been shown to exacerbate neurological disease in mice, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Z-Pro-pro-aldehyde-dimethyl acetal binds to microglia cells and induces reactive oxygen species production, which may contribute to cell damage. This toxin also diffracts light at a wavelength of 630 nm when exposed to X-rays, making it useful for labeling lysosomal enzymes in tissue sections or cell supernatants.

Chemical properties

• Molecular weight: 376.45 g/mol
• Formula: C₂₀H₂₈N₂O₅
• Purity: Min. 95%