1-(2-Phenoxyethyl)piperazine

Ref. 3D-FP123488

Product Information

• Name: 1-(2-Phenoxyethyl)piperazine
• Synonyms: piperazine, 1-(2-phenoxyethyl)-
• Brand: Biosynth
• Description: 1-(2-Phenoxyethyl)piperazine is an antipsychotic agent that has been evaluated for its anticancer potential. It is a potent antagonist of the 5-HT2A receptor, with no affinity for other serotonin receptors. Clozapine, a structurally related agent, has been shown to have some anticancer activity in animal models. However, 1-(2-Phenoxyethyl)piperazine may be more effective than clozapine because it does not bind to the D4 dopamine receptor or the serotonin transporter (SERT). In addition, 1-(2-Phenoxyethyl)piperazine is less toxic than clozapine and has a longer half-life. The nature of 1-(2-Phenoxyethyl)piperazine's anticancer activity remains unclear.

Chemical properties

• Molecular weight: 206.28 g/mol
• Formula: C₁₂H₁₈N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C12H18N2O/c1-2-4-12(5-3-1)15-11-10-14-8-6-13-7-9-14/h1-5,13H,6-11H2
• InChI key: InChIKey=PTJSLCXRMMGRLY-UHFFFAOYSA-N
• SMILES: c1ccc(OCCN2CCNCC2)cc1