D-Proline

CAS: 344-25-2

Ref. 3D-FP12674

Product Information

• Name: D-Proline
• Synonyms: D-Pyrrolidine-2-carboxylic acid, (+)-(R)-Proline, (2R)-Pyrrolidin-1-ium-2-carboxylate, (2R)-Pyrrolidine-2-carboxylic acid, (R)-2-Carboxypyrrolidine, (R)-Pyrrolidine-2-carboxylic acid, <span class="text-smallcaps">D</span>-(+)-Proline, D-(+)-Prolin, D-(+)-prolina, H-D-Pro-OH, Proline, <span class="text-smallcaps">D</span>-, Proline, D-, D-(+)-Proline

Description

D-Proline is a non-essential amino acid that can be synthesized by the body. It is a racemic mixture of the two stereoisomers, L-proline and D-proline. Research has shown that D-proline inhibits the enzyme racemase, which converts L-proline to D-proline. Racemase inhibition leads to an accumulation of L-proline, which may reduce disease activity in some cases. D-Proline also inhibits liver cells and trigeminal nerve cells, leading to decreased pain. The asymmetric synthesis of picolinic acid from D-pyridoxal 5'-phosphate catalyzed by prolinase occurs at a pH optimum around 2.8. This reaction is used as a model system for studying chemical biology and antimicrobial peptides.
D-Proline can be found in E coli K12 and other bacteria with analytical chemistry techniques such as gas chromatography mass spectrometry (GC

• Brand: Biosynth

Chemical properties

• Molecular weight: 115.13 g/mol
• Formula: C₅H₉NO₂
• Color/Form: Powder
• InChI: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
• InChI key: InChIKey=ONIBWKKTOPOVIA-SCSAIBSYSA-N
• SMILES: O=C(O)[C@H]1CCCN1