Propynal, stabilised with Hydroquinone
CAS:
Ref. 3D-FP13241
Product Information
Propynal, stabilised with Hydroquinone is a drug that is used for the treatment of autoimmune diseases. It is an irreversible inhibitor of monoamine oxidase-A (MAO-A) and MAO-B and inhibits the activity of these enzymes in rat liver microsomes. Propynal, stabilised with Hydroquinone also inhibits mitochondrial membrane potential. The thermodynamic data show that propynal has a high affinity for hydroxyl groups. The reactivity of propynal is determined by the nucleophilic character of the hydroxyl group, which can be either electrophilic or nucleophilic in nature. The reaction mechanism involves a transfer reaction between methyl ethyl trifluoroacetate and propynol to form methyl ethyl trifluoroacetate hydroquinone oxime. This type of reaction is reversible and can be inhibited by pargyline.
Chemical properties
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