3-Piperidin-4-yl-1h-indole

CAS: 17403-09-7

Ref. 3D-FP147717

Product Information

• Name: 3-Piperidin-4-yl-1h-indole
• Synonyms: 1H-Indole, 3-(4-piperidinyl)-, 3-(4-Piperidinyl)-1H-indole, 3-(4-Piperidyl)-1H-indole, 3-(4-Piperidyl)indole, 3-(Piperidin-4-yl)indole, 3-(piperidin-1-yl)-1H-indole, 4-(1H-Indol-3-yl)piperidine, 4-(1H-indol-3-yl)piperidinium, 4-(3-Indolyl)piperidine, Indole, 3-(4-piperidyl)-, Ru 22424

Description

3-Piperidin-4-yl-1H-indole (3P4I) is a synthetic drug that inhibits the reuptake of serotonin and acts as an antidepressant. It has been shown to be effective in animal models of depression and other psychiatric disorders, including psychotic disorders. 3P4I stimulates the synthesis of 5-HT in mammalian cells, which leads to increased levels of serotonin in the brain. This compound also interacts with the 5-HT1A receptor, inducing a response pathway that inhibits neuronal firing. 3P4I has been shown to cross-react with the 5-HT7 receptor, which may lead to its antidepressant effects. 3P4I binds to a site on human liver enzymes that is similar to that for selective serotonin reuptake inhibitors (SSRIs). The molecular modeling studies show that 3P4I has a high binding affinity for this site.

• Brand: Biosynth

Chemical properties

• Molecular weight: 200.28 g/mol
• Formula: C₁₃H₁₆N₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H16N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-4,9-10,14-15H,5-8H2
• InChI key: InChIKey=KAIRZPVWWIMPFT-UHFFFAOYSA-N
• SMILES: c1ccc2c(C3CCNCC3)c[nH]c2c1