1-Phenyl-piperidine
CAS: 4096-20-2
Ref. 3D-FP148660
| 1g | 136.00 € | ||
| 2g | 149.00 € | ||
| 5g | 256.00 € | ||
| 10g | 425.00 € | ||
| 25g | 739.00 € |
Product Information
- N-Phenylpiperidine
- Nsc 53427
- Piperidine, 1-phenyl-
- 1-Phenylpiperidine
- 1-Phenylpiperidine
1-Phenyl-piperidine is a psychoactive compound that has been shown to have strong binding affinity for the κ-opioid receptors. It has also been shown to increase locomotor activity in mice and produce hallucinations. 1-Phenyl-piperidine has a number of biological properties including inhibition of dopamine uptake, induction of myocardial infarcts, and toxicity to the ischemic brain. It binds with high affinity to the multidrug efflux pumps such as P-glycoprotein (Pgp) and MDR1, which are responsible for removing drugs from cells. Pgp is induced by cytochrome P450 3A4 (CYP3A4) inhibitors such as ketoconazole, erythromycin, fluconazole, itraconazole, clarithromycin, telithromycin, nefazodone, and grapefruit juice.
Chemical properties
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