Potassium canrenoate

CAS: 2181-04-6

Ref. 3D-FP149848

Product Information

• Name: Potassium canrenoate
• Synonyms: 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid potassium salt, 17α-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, monopotassium salt, 17α-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, potassium salt, Aldadiene Kalium, Aldadiene potassium, Aldadiene potassium salt, Canrenoate Potassium, Cb 8109, Kanrenol, MF 465 a, Potassium 17-hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylate, Potassium 3-(17β-hydroxy-3-oxoandrosta-4,6-dien-17-yl)propionate, Potassium 3-(3-oxo-17β-hydroxy-4,6-androstadien-17α-yl)propionate, Potassium aldadiene, Potassium β-(3-oxo-17β-hydroxyandrosta-4,6-dien-17α-yl)propionate, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, monopotassium salt, (17α)-, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, potassium salt (1:1), (17α)-, Sc 14266, Sc 14266/371, Soldactona, Soldactone, Soludactone, Venactone, potassium 3-[(10R,13S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate (non-preferred name), potassium 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate (non-preferred name)

Description

Potassium canrenoate is a potassium salt of canrenoic acid, which is an imidazopyridine that has been shown to be beneficial in the treatment of cardiovascular diseases. It binds to the adenyl cyclase receptor, inhibiting production of cyclic AMP, and thereby decreasing the uptake of glucose and fatty acids into muscle cells. In addition, potassium canrenoate increases blood flow by dilating coronary arteries, improves cardiac contractility and reduces myocardial oxygen demand. The hyperglycemic effect seen with potassium canrenoate may be due to its ability to inhibit insulin release from pancreatic beta-cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 396.56 g/mol
• Formula: C₂₂H₂₉KO₄
• Purity: Min. 98 Area-%
• Color/Form: Powder