2-Phenyl-malononitrile

CAS: 3041-40-5

Ref. 3D-FP152726

Product Information

• Name: 2-Phenyl-malononitrile
• Brand: Biosynth
• Description: 2-Phenyl-malononitrile is an amide with a malonic acid group. It is a nucleophilic agent that inhibits the activity of histone deacetylases (HDACs). 2-Phenyl-malononitrile binds to the zinc ion in the active site of HDACs, preventing them from catalyzing the removal of acetyl groups from lysine residues on histones and other proteins. The use of 2-phenyl-malononitrile as an inhibitor has been shown to be effective against lipid kinases and protein targets of oxidative stress. It also inhibits transfer reactions involving oxygen nucleophiles, such as hydrochloric acid or carbonyl compounds. In addition, 2-phenyl-malononitrile has been shown to have pharmaceutical preparations for inhibiting cancer cell growth by targeting proteins involved in transcriptional regulation.

Chemical properties

• Molecular weight: 142.16 g/mol
• Formula: C₉H₆N₂
• Purity: Min. 95%
• Color/Form: Solid