Pipecolic acid

CAS: 3105-95-1

Ref. 3D-FP15563

Product Information

• Name: Pipecolic acid
• Synonyms: piperidine-2-carboxylic acid.(2S) 2-Piperidinecarboxylic acid, (-)-Pipecolic acid, (-)-Pipecolinic acid, (2S)-2-Piperidinecarboxylic acid, (2S)-Piperidin-1-ium-2-carboxylate, (2S)-piperidine-2-carboxylate, (2S)-piperidine-2-carboxylic acid, (S)-(-)-2-Piperidinecarboxylic Acid, (S)-(-)-Pipecolic acid, (S)-Pipecolinic acid, (S)-Piperidine-2-carboxylic acid, 2-Piperidinecarboxylic acid (2S)-, 2-Piperidinecarboxylic acid, (S)-, <span class="text-smallcaps">L</span>-(-)-Pipecolic acid, <span class="text-smallcaps">L</span>-Homoproline, <span class="text-smallcaps">L</span>-Pipecolinic acid, <span class="text-smallcaps">L</span>-Piperidine-2-carboxylic acid, L(-)-2-Pipecolinic acid, L(-)-Pipecolinic Acid, L-Homoproline, NSC 93089, Pipecolic acid, (S)-(-)-

Description

Pipecolic acid is a metabolite of tryptophan that has been shown to inhibit the proliferation of pluripotent cells in vitro. Pipecolic acid was also shown to have a significant effect on the reaction mechanism of dinucleotide phosphate, which is essential for the synthesis of DNA and RNA. Pipecolic acid can be synthesized from picolinic acid through an amide bond formation. This compound is also found in wild-type strains as well as cancerous and infectious strains of bacteria. Pipecolic acid inhibits bacterial growth by binding to the active site of specific enzymes, such as methionine adenosyltransferase and ribonucleotide reductase, leading to the inhibition of protein synthesis and cell division. It has been shown to inhibit leukemia inhibitory factor (LIF) activity in vitro, suggesting that it may be involved in urinary infections.
Pipecolic acid can also be prepared using preparative high-performance liquid chromatography (prepar

• Brand: Biosynth

Chemical properties

• Molecular weight: 129.16 g/mol
• Formula: C₆H₁₁NO₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1
• InChI key: InChIKey=HXEACLLIILLPRG-YFKPBYRVSA-N
• SMILES: O=C(O)[C@@H]1CCCCN1