(7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate

CAS: 156311-83-0

Ref. 3D-FP15579

Product Information

• Name: (7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
• Synonyms: PyAOP, (7-Azabenzotriazol-1-YLOXY)TRIPYRROLIDINO-phosphonium hexafluorophosphate, (7-Azabenzotriazol-1-yloxy)tripyrrolidinophospho, (7-Azabenzotriazole-1-YLOXY)TRIPYRROLIDI, (7-Azabenzotriazole-1-YLOXY)Tripyrrolidinophosphonium hexafluorophosphate, 3H-1,2,3-Triazolo[4,5-b]pyridine, phosphonium deriv., 7-Azabenzotriazol-1-YLOXY-TRIS-(PYRROLIDINO)phosphonium hexafluorophosphate, O-(1,2-Dihydro-2-oxo-pyridyl]-N,N,N',N'-tetramethyluronium hexafluorophosphate, PY (7-Azabenzotriazol-1-YLOXY)Tripyrrolidinophosphonium hexafluorophosphate, Phosphonium, tri-1-pyrrolidinyl(3H-1,2,3-triazolo[4,5-b]pyridin-3-yloxy)-, hexafluorophosphate(1-), Phosphorus(1+), (3-hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-), Phosphorus(1+), [3-(hydroxy-κO)-3H-1,2,3-triazolo[4,5-b]pyridinato]tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1), Pyaop, [(7-Azabenzotriazol-1-yl)oxy]tris(pyrrolidino)phosphonium hexafluorophosphate, tripyrrolidin-1-yl(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yloxy)phosphonium hexafluorophosphate

Description

PyAOP is a phosphonium salt derivative from HOAt used a peptide coupling reagent. PyAOP is stable as a solid and in DMF solution, effective in solid-phase and solution-based peptide synthesis, successful with sterically hindered amino acids, in the formation of cyclic peptides and in the solid-phase synthesis of fluorescently labelled peptides. PyAOP achieves excellent yields at good reaction rates and suppresses racemisation. PyAOP is the pyrrolidino analogue of AOP and was designed with the aim of generating a less-toxic by-product than HMPA, which is produced with AOP.

• Brand: Biosynth

Chemical properties

• Molecular weight: 521.38 g/mol
• Formula: C₁₇H₂₇F₆N₇OP₂
• Purity: Min. 98 Area-%
• Color/Form: White Powder