Pyrazine-2-carboxylic acid
CAS: 98-97-5
Ref. 3D-FP15650
1kg | 501.00 € | ||
2kg | 895.00 € | ||
100g | 136.00 € | ||
250g | 234.00 € | ||
500g | 352.00 € |
Product Information
- 1,4-Diazinecarboxylic acid
- 2-Carboxyl-pyrazine
- 2-Carboxypyrazine
- 2-Pyrazinecarboxylic
- 2-Pyrazinoic acid
- Acide Pyrazine-2-Carboxylique
- Acido Pirazina-2-Carboxilico
- Nsc 13146
- Nsc 27192
- Paradiazinecarboxylic acid
- See more synonyms
- Pyrazin-2-carbonsaure
- Pyrazine-2-formic acid
- Pyrazinecarboxylic acid
- Pyrazinic acid
- Pyrazinoic acid
- Rarechem Al Bo 0493
- Timtec-Bb Sbb000051
Pyrazine-2-carboxylic acid is a potent inhibitor of bacterial x-lactamase. It was found that the inhibition of x-lactamase by pyrazine-2-carboxylic acid could be attributed to hydrogen bonding interactions with the active site of the enzyme and a high rate constant for the reaction. The antibacterial efficacy of pyrazine-2-carboxylic acid against wild type Streptococcus pneumoniae and methicillin resistant Staphylococcus aureus (MRSA) was tested and found to be comparable to that of benzylpenicillin. Pyrazine-2-carboxylic acid also has biological properties, such as an inhibitory effect on protein synthesis in bacteria, which may be due to its ability to bind to ribosomes.
Chemical properties
Technical inquiry about: 3D-FP15650 Pyrazine-2-carboxylic acid
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