Pyrazine-2-carboxylic acid

CAS: 98-97-5

Ref. 3D-FP15650

Product Information

• Name: Pyrazine-2-carboxylic acid
• Brand: Biosynth
• Description: Pyrazine-2-carboxylic acid is a potent inhibitor of bacterial x-lactamase. It was found that the inhibition of x-lactamase by pyrazine-2-carboxylic acid could be attributed to hydrogen bonding interactions with the active site of the enzyme and a high rate constant for the reaction. The antibacterial efficacy of pyrazine-2-carboxylic acid against wild type Streptococcus pneumoniae and methicillin resistant Staphylococcus aureus (MRSA) was tested and found to be comparable to that of benzylpenicillin. Pyrazine-2-carboxylic acid also has biological properties, such as an inhibitory effect on protein synthesis in bacteria, which may be due to its ability to bind to ribosomes.

Chemical properties

• Molecular weight: 124.1 g/mol
• Formula: C₅H₄N₂O₂
• Purity: Min. 95%
• Color/Form: Powder