Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

CAS: 25940-35-6

Ref. 3D-FP16388

Product Information

• Name: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
• Brand: Biosynth
• Description: Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid is a pyrimidine analog and an electron transfer agent. It is a potent inhibitor of the enzyme dehydrogenase, which catalyzes the conversion of nicotinamide adenine dinucleotide (NAD) to nicotinamide adenine dinucleotide phosphate (NADP). Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid has been shown to have anti-inflammatory properties and also inhibits the production of b-raf protein. This drug has also been shown to be a potent inhibitor of mitochondrial electron transport in cancer cells. Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid binds to the metal centers in mitochondria, thereby inhibiting oxidative phosphorylation and reducing ATP synthesis. This ultimately leads to cell death by apoptosis.

Chemical properties

• Molecular weight: 163.13 g/mol
• Formula: C₇H₅N₃O₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C7H5N3O2/c11-7(12)5-4-9-10-3-1-2-8-6(5)10/h1-4H,(H,11,12)
• InChI key: InChIKey=HNYVPKNVKSTVJO-UHFFFAOYSA-N
• SMILES: O=C(O)c1cnn2cccnc12