2-Palmitoylglycerol

CAS: 23470-00-0

Ref. 3D-FP167393

Product Information

• Name: 2-Palmitoylglycerol
• Synonyms: 1,3-Dihydroxypropan-2-yl palmitate, 2-Hexadecanoyl glycerol, 2-Monohexadecanoylglycerol, 2-Monopalmitin, 2-Monopalmitoyl-sn-glycerol, 2-Monopalmitoylglycerol, 2-Palmitoyl-rac-glycerol, Glycerol, 2-palmitate, Glycerol-β-palmitate, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, Palmitic acid β-monoglyceride, Palmitin, 2-mono, beta-Monopalmitin, β-Monopalmitin

Description

2-Palmitoylglycerol is a monoacylglycerol that is synthesized from the breakdown of dietary fats. It is also synthesized in tissues through the action of phospholipase A2 and diacylglycerol acyltransferase. 2-Palmitoylglycerol has been shown to bind to the cannabinoid receptor type 1 (CB1), which leads to activation of peroxisome proliferator-activated receptor α (PPARα). This activation induces gene expression changes that lead to increased fatty acid oxidation and decreased triglyceride synthesis in liver cells. 2-Palmitoylglycerol has been shown to reduce body weight gain and increase insulin sensitivity in mice models on high fat diets.
2-Palmitoylglycerol has also been shown to increase butyrate, a short chain fatty acid, levels in rats with metabolic disorders.

• Brand: Biosynth

Chemical properties

• Molecular weight: 330.5 g/mol
• Formula: C₁₉H₃₈O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-18(16-20)17-21/h18,20-21H,2-17H2,1H3
• InChI key: InChIKey=BBNYCLAREVXOSG-UHFFFAOYSA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)OC(CO)CO