PNU 142586

CAS: 368891-70-7

Ref. 3D-FP175532

Product Information

• Name: PNU 142586
• Brand: Biosynth
• Description: PNU 142586 is a drug that inhibits protein synthesis by binding to the 50S ribosomal subunit. It has been shown to be effective against infectious diseases, including tuberculosis and HIV. PNU 142586 also reduces the incidence of drug reactions in patients with hepatic impairment. The concentration-time curve for PNU 142586 shows that it is rapidly absorbed and eliminated from the body, which may be due to its rapid metabolism by esterases. Animal studies have shown that PNU 142586 is not toxic to humans, but it has been shown to cause liver damage in rats. Clinical studies have found that PNU 142586 is effective at treating tuberculosis in humans, although more research into adverse effects on other organs is needed. Urea nitrogen levels were found to increase during treatment with PNU 142586, which may be due to its effect on protein synthesis.br>

Chemical properties

• Molecular weight: 369.35 g/mol
• Formula: C₁₆H₂₀FN₃O₆
• Purity: Min. 95%