D-Penicillamine

CAS: 52-67-5

Ref. 3D-FP26792

Product Information

• Name: D-Penicillamine
• Synonyms: 3-Mercapto-D-valine(2S)-2-Amino-3-methyl-3-sulfanylbutanoic acid(S)-3,3-DimethylcysteineH-D-Pen-OH, (-)-Penicillamine, (2S)-2-Azaniumyl-3-methyl-3-sulfanylbutanoate, (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid, (S)-3,3-Dimethylcysteine, (S)-Penicillamine, 2-Amino-3-mercapto-3-methylbutanoic acid, 3,3-Dimethyl-D-cysteine, 3-Mercapto-<span class="text-smallcaps">D</span>-valine, 3-Mercapto-D-valine, <span class="text-smallcaps">D</span>-(-)-Penicillamine, <span class="text-smallcaps">D</span>-3-Mercaptovaline, <span class="text-smallcaps">D</span>-Mercaptovaline, <span class="text-smallcaps">D</span>-Penamine, <span class="text-smallcaps">D</span>-Valine, 3-mercapto-, Artamin, Cuprenil, Cuprimine, Cupripen, D-3-Mercaptovaline, D-Mercaptovaline, D-Penamine, D-Penicillin, D-Valine, 3-mercapto-, D-minus-penicillamine free base, DPA, Depamine, Depen, Dimethylcysteine, H-D-Pen-OH, Kuprenil, Mercaptyl, Metalcaptase, N,N-dimethylcysteine, Nsc 81549, Pendramine, Penicilamina, Penicillamin, Penicillamine, D-(-)-, Penicilllamine, Perdolat, Reduced <span class="text-smallcaps">D</span>-penicillamine, Reduced D-penicillamine, Reduced penicillamine, Sufirtan, Trolovol, Valine, 3-mercapto-, <span class="text-smallcaps">D</span>-, Valine, 3-mercapto-, D-, β-Thiovaline

Description

D-Penicillamine is a nonsteroidal anti-inflammatory drug that is used to treat bowel disease, including ulcerative colitis and Crohn's disease. It has also been used as a treatment for schizophrenia that is unresponsive to other treatments. D-Penicillamine binds covalently to reactive oxygen species (ROS), thereby preventing their interaction with proteins and DNA. The binding of ROS by D-penicillamine can be monitored using electrochemical impedance spectroscopy (EIS). The compound has also been shown to reduce the expression of bcl-2 protein in human cells, which may result in increased oxidative injury and rates of cell proliferation. D-Penicillamine has been shown to have therapeutic benefits for patients with primary sclerosing cholangitis, myocardial infarcts, or preparative high performance liquid chromatography (HPLC) analysis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 149.21 g/mol
• Formula: C₅H₁₁NO₂S
• Purity: Min 97%
• Color/Form: White Powder
• InChI: InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1
• InChI key: InChIKey=VVNCNSJFMMFHPL-VKHMYHEASA-N
• SMILES: CC(C)(S)[C@@H](N)C(=O)O