3,3-Pentamethylene glutarimide

CAS: 1130-32-1

Ref. 3D-FP26807

Product Information

• Name: 3,3-Pentamethylene glutarimide
• Synonyms: 2,4-Dioxo-3-azaspiro[5.5]undecane1,1-Cyclohexanediacetimide3-Azaspiro[5.5]undecane-2,4-dione
• Brand: Biosynth
• Description: 3,3-Pentamethylene glutarimide is an amide that can be used for the synthesis of gabapentin. It is synthesized from cyclohexanone and hydrochloric acid in a reaction that utilizes ammonium salt as a catalyst. 3,3-Pentamethylene glutarimide reacts with deionized water to form the monamide product. The filtrate is collected and concentrated before it is cooled to produce gabapentin.

Chemical properties

• Molecular weight: 181.23 g/mol
• Formula: C₁₀H₁₅NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H15NO2/c12-8-6-10(7-9(13)11-8)4-2-1-3-5-10/h1-7H2,(H,11,12,13)
• InChI key: InChIKey=FNIPRNMPSXNBDI-UHFFFAOYSA-N
• SMILES: O=C1CC2(CCCCC2)CC(=O)N1