Product Information
Name:JWH 018
Controlled Product
Synonyms:
- 1-Naphthalenyl(1-pentyl-1H-indol-3-yl)methanone1-Pentyl-3-(1-naphthoyl)indole
Brand:Biosynth
Description:JWH-018 is a synthetic cannabinoid receptor agonist with a strong affinity for the CB1 and CB2 receptors (EC50 = 102 nM and 133 nM, respectively)1. Binding to the receptors triggers a reduction of intracellular cAMP levels by inhibition of adenylate cyclase. In vivo studies on experimental mouse models showed similar responses as THC, including hypothermia, catalepsy, and hypolocomotor effects2. In vitro, JWH-018 impaired electrically-induced synaptic transmission as well as LTP and glutamate/GABA release in ex vivo hippocampal slices. All behavioural and neurochemical effects could be prevented by pre-treatment with a CB1 receptor antagonist3.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:341.45 g/mol
Formula:C24H23NO
Purity:Min. 95%
Technical inquiry about: JWH 018
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please add the desired products to your cart and manage the request from there. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.