Product Information
Name:Perindopril benzyl ester
Synonyms:
- (2S,3aS,7aS)-1-[(2S)-2-[[(1R)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid benzyl ester
Brand:Biosynth
Description:Perindopril is a prodrug that is metabolized to its active form, ramipril. It belongs to the group of angiotensin-converting enzyme inhibitors and is used for the treatment of hypertension. The hydroxy group reacts with benzyl chloride in an organic solvent, forming a molecule with a chloride group. This reaction takes place in a reaction vessel that signifies stereoselectively, meaning only one stereoisomer is produced. Perindopril undergoes an acidic amino function, which makes it more difficult for this drug to be absorbed through the gastrointestinal system. In addition, perindopril binds to thionyl chloride or chlorine in anhydrous sodium, which makes it more soluble in water.
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Chemical properties
Molecular weight:458.59 g/mol
Formula:C26H38N2O5
Purity:Min. 95%
InChI:InChI=1S/C26H38N2O5/c1-4-11-21(25(30)32-5-2)27-18(3)24(29)28-22-15-10-9-14-20(22)16-23(28)26(31)33-17-19-12-7-6-8-13-19/h6-8,12-13,18,20-23,27H,4-5,9-11,14-17H2,1-3H3
InChI key:InChIKey=ZNAYHAPFFQRGES-UHFFFAOYSA-N
SMILES:CCCC(NC(C)C(=O)N1C(C(=O)OCc2ccccc2)CC2CCCCC21)C(=O)OCC
Technical inquiry about: Perindopril benzyl ester
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