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Phenyl 2-chloroethyl ether
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Phenyl 2-chloroethyl ether

CAS: 622-86-6

Ref. 3D-FP26898

10g
136.00 €
25g
172.00 €
50g
258.00 €
100g
387.00 €
250g
690.00 €
Estimated delivery in United States, on Friday 17 Jan 2025

Product Information

Name:
Phenyl 2-chloroethyl ether
Synonyms:
  • b-Chlorophenetole1-Chloro-2-phenoxyethane2-Phenoxyethyl chloride
  • (2-Chloroethoxy)benzene
  • 1-Chloro-2-phenoxyethane
  • 1-Phenoxy-2-chloroethane
  • 2-Chloroethyl Phenyl Ether
  • 2-Phenoxyethyl chloride
  • Benzene, (2-chloroethoxy)-
  • NSC 1073
  • Phenetole, β-chloro-
  • β-Chlorophenetole
  • See more synonyms
Description:

Phenyl 2-chloroethyl ether is a chlorinated derivative of the chemical compound endoxifen. It is a potent antiestrogen, with IC50 values in the nanomolar range. Phenyl 2-chloroethyl ether has been shown to inhibit cell proliferation in vitro and in vivo by blocking estrogen receptors and inducing apoptotic cell death. The drug also has an inorganic acid terminus, which prevents it from being metabolized by esterases or glucuronidases, leading to its prolonged therapeutic effect.

Phenyl 2-chloroethyl ether is used clinically as a cancer chemotherapeutic agent. It targets cancer cells that depend on estrogen for growth by binding to the estrogen receptor alpha (ERα) and blocking estrogen signaling pathways, which leads to tumor shrinkage. This drug also inhibits the uptake of cancer drugs such as doxorubicin into cells and prevents the synthesis of DNA and RNA.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
156.61 g/mol
Formula:
C8H9ClO
Purity:
Min. 95%
Color/Form:
Clear Liquid
InChI:
InChI=1S/C8H9ClO/c9-6-7-10-8-4-2-1-3-5-8/h1-5H,6-7H2
InChI key:
InChIKey=VQUYNUJARXBNPK-UHFFFAOYSA-N
SMILES:
ClCCOc1ccccc1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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