N-Phenyl isobutyrylacetamide

CAS: 124401-38-3

Ref. 3D-FP26900

Product Information

• Name: N-Phenyl isobutyrylacetamide
• Synonyms: N-Phenyl-4-methyl-3-oxopentanamide4-Methyl-3-oxopentanoic acid anilide
• Brand: Biosynth
• Description: N-Phenyl isobutyrylacetamide (NPIBA) is a synthetic compound that has been shown to be an effective and selective reagent for the Friedel-Crafts acylation of aromatic amines with carbonyl compounds. The reaction is highly stereoselective and can be used to manufacture various pharmaceuticals. NPIBA is relatively stable, but can react with chloride ions in water or organic solvents such as chloroform. The reaction time depends on the type of solvent used, but it typically occurs in less than an hour. This reaction can also be carried out with recycled NPIBA and organocatalysts.

Chemical properties

• Molecular weight: 205.25 g/mol
• Formula: C₁₂H₁₅NO₂
• Purity: Min. 95%