2-Phenylacetophenone

CAS: 451-40-1

Ref. 3D-FP26930

Product Information

• Name: 2-Phenylacetophenone
• Synonyms: 1,2-Diphenylethanone1,2-Diphenylethan-1-oneDeoxybenzoin
• Brand: Biosynth

Description

2-Phenylacetophenone is a synthetic compound that has been shown to be cytotoxic and significantly inhibit the growth of bacteria. 2-Phenylacetophenone binds to fatty acids in the cell membrane and forms covalent linkages with them, leading to the permeabilization of the cell membrane. This leads to bacterial death because without a functional cell membrane, cells cannot maintain homeostasis. The mechanism for this is not fully understood but it is believed that 2-phenylacetophenone binds to toll-like receptor 4 (TLR4) on macrophages, which triggers an inflammatory response. 2-Phenylacetophenone also reacts with hydroxyl groups on DNA and may interfere with DNA repair mechanisms.

Chemical properties

• Molecular weight: 196.24 g/mol
• Formula: C₁₄H₁₂O
• Purity: Min. 95%
• Color/Form: Red Powder
• InChI: InChI=1S/C14H12O/c15-14(13-9-5-2-6-10-13)11-12-7-3-1-4-8-12/h1-10H,11H2
• InChI key: InChIKey=OTKCEEWUXHVZQI-UHFFFAOYSA-N
• SMILES: O=C(Cc1ccccc1)c1ccccc1